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Laboratory for MetaSystems Research, RIKEN Quantitative Biology Center


[ English / 日本語 (Japanese) ]

Contents

Introduction

Our main area of research is the analysis of various human health-and environmental- related metagenomics systems. We are developing powerful, high-throughput open-source tools and databases for the comprehensive analysis of metagenomic and bacterial genomic sequence data. The ultimate goal of our research will be to model and predict the behavior and interactions of whole environments of organisms.

Recent Highlights

  • "Complete genome sequences of rat and mouse segmented filamentous bacteria, a potent inducer of Th17 cell differentiation." Prakash T, Oshima K, Morita H, Fukuda S, Imaoka A, Kumar N, Sharma VK, Takahashi M, Saitou N, Taylor TD, Ohno H, Umesaki Y, Hattori M. Cell Host & Microbe 10(3):273-284. (September 15, 2011) PMID 21925114
  • "Genomes of two chronological isolates (Helicobacter pylori 2017 and 2018) of the West African Helicobacter pylori strain 908 obtained from a single patient." Avasthi TS, Devi SH, Taylor TD, Kumar N, Baddam R, Kondo S, Suzuki Y, Lamouliatte H, Mégraud F, Ahmed N. J Bacteriol 193(13):3385-3386. (July, 2011) PMID 21515762
  • "Bifidobacteria can protect from enteropathogenic infection through production of acetate." Fukuda S, Toh H, Hase K, Oshima K, Nakanishi Y, Yoshimura K, Tobe T, Clarke JM, Topping DL, Suzuki T, Taylor TD, Itoh K, Kikuchi J, Morita H, Hattori M, Ohno H. Nature 469(7331):543-547. (January 26, 2011) PMID 21270894
  • "Expression of conjoined genes: another mechanism for gene regulation in eukaryotes." Prakash T, Sharma VK, Adati N, Ozawa R, Kumar N, Nishida Y, Fujikake T, Takeda T, Taylor TD. PLoS ONE 5(10):1-9 e13284. (October 12, 2010) PMID 20967262

Projects

Tools and Resources

  • MetaBioME: a database to explore commercially useful enzymes in metagenomic datasets
  • ConjoinG - Database of Human Conjoined Genes

Members

Meetings and Events

Other Information


[ English / 日本語 (Japanese) ]
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